{"id":6886,"date":"2011-06-03T13:00:49","date_gmt":"2011-06-03T20:00:49","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/cosmicvariance\/?p=6886"},"modified":"2011-06-03T13:00:49","modified_gmt":"2011-06-03T20:00:49","slug":"dna-takes-square-roots","status":"publish","type":"post","link":"https:\/\/preposterousuniverse.com\/blog\/2011\/06\/03\/dna-takes-square-roots\/","title":{"rendered":"DNA Takes Square Roots"},"content":{"rendered":"<p>Around these parts we&#8217;ve been known to discuss whether it makes any sense to say that <a href=\"http:\/\/blogs.discovermagazine.com\/cosmicvariance\/2008\/01\/10\/is-the-universe-a-computer\/\">the universe is a computer<\/a>.  There&#8217;s little doubt, of course, that <em>parts<\/em> of the universe are computer-like.  And in case you are wondering, you can now officially remove DNA from your personal list of &#8220;things I suspect are not computers.&#8221;<\/p>\n<p>Caltech researchers <a href=\"http:\/\/www.dna.caltech.edu\/DNApeople.html\">Lulu Qian and Erik Winfree<\/a> have managed to coax 130 strands of DNA into performing what is unquestionably a calculation:  taking the square root of a number.  (<a href=\"http:\/\/arstechnica.com\/science\/news\/2011\/06\/dna-logic-gates-calculate-a-square-root-using-130-different-molecules.ars\">Ars Technica post<\/a>; <a href=\"http:\/\/www.sciencemag.org\/content\/332\/6034\/1196\"><em>Science<\/em> paper<\/a> behind paywall; <a href=\"http:\/\/rsif.royalsocietypublishing.org\/content\/early\/2011\/02\/03\/rsif.2010.0729.full\">open-access background paper<\/a>.)  Not a big number: we&#8217;re talking about four-digit binary numbers, so 15 at the biggest.  And not very efficiently: with prodding, the calculation took eight hours.  Moore&#8217;s Law isn&#8217;t really in danger here.<\/p>\n<p>Still, pretty cool stuff.  Mostly it&#8217;s interesting because it seems scalable:  the authors claim that this kind of circuit architecture could be made much larger.  It&#8217;s not the first biochemical circuit; RNA and bacterial colonies have been made into logic gates.  But it&#8217;s the first to do something as elaborate as taking a square root.<\/p>\n<p>Best of all, the authors decided to illustrate their method for a wide audience by means of a &#8230; whimsical YouTube video!  Let&#8217;s hope this idea catches on.<\/p>\n<div class=\"lyte-wrapper\" title=\"The seesaw magic book: the computational power of DNA molecules\" style=\"width:640px;max-width:100%;margin:5px;\"><div class=\"lyMe\" id=\"WYL_G2Ljgkh_v40\" itemprop=\"video\" itemscope itemtype=\"https:\/\/schema.org\/VideoObject\"><div><meta itemprop=\"thumbnailUrl\" content=\"https:\/\/i.ytimg.com\/vi\/G2Ljgkh_v40\/hqdefault.jpg\" \/><meta itemprop=\"embedURL\" content=\"https:\/\/www.youtube.com\/embed\/G2Ljgkh_v40\" \/><meta itemprop=\"duration\" content=\"PT12M46S\" \/><meta itemprop=\"uploadDate\" content=\"2011-06-02T03:01:12Z\" \/><\/div><div id=\"lyte_G2Ljgkh_v40\" data-src=\"https:\/\/i.ytimg.com\/vi\/G2Ljgkh_v40\/hqdefault.jpg\" class=\"pL\"><div class=\"tC\"><div class=\"tT\" itemprop=\"name\">The seesaw magic book: the computational power of DNA molecules<\/div><\/div><div class=\"play\"><\/div><div class=\"ctrl\"><div class=\"Lctrl\"><\/div><div class=\"Rctrl\"><\/div><\/div><\/div><noscript><a href=\"https:\/\/youtu.be\/G2Ljgkh_v40\" rel=\"nofollow\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/i.ytimg.com\/vi\/G2Ljgkh_v40\/0.jpg\" alt=\"The seesaw magic book: the computational power of DNA molecules\" width=\"640\" height=\"340\" \/><br \/>Watch this video on YouTube<\/a><\/noscript><meta itemprop=\"description\" content=\"A whimsical explanation of recent research developing molecular systems that perform information processing tasks. Yes, it&#039;s real. No, there&#039;s no magic. Reference: &quot;Scaling Up Digital Circuit Computation with DNA Strand Displacement Cascades,&quot; Lulu Qian and Erik Winfree, Science, June 3, 2011 Animation and Narration: Lulu Qian Music: Donde Voy, on The Daydream - A Sleeping Forest Stock images from iStockphoto\"><\/div><\/div><div class=\"lL\" style=\"max-width:100%;width:640px;margin:5px;\"><\/div> <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Around these parts we&#8217;ve been known to discuss whether it makes any sense to say that the universe is a computer. There&#8217;s little doubt, of course, that parts of the universe are computer-like. And in case you are wondering, you can now officially remove DNA from your personal list of &#8220;things I suspect are not [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[28,34],"tags":[],"class_list":["post-6886","post","type-post","status-publish","format-standard","hentry","category-science","category-technology"],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/preposterousuniverse.com\/blog\/wp-json\/wp\/v2\/posts\/6886","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/preposterousuniverse.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/preposterousuniverse.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/preposterousuniverse.com\/blog\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/preposterousuniverse.com\/blog\/wp-json\/wp\/v2\/comments?post=6886"}],"version-history":[{"count":0,"href":"https:\/\/preposterousuniverse.com\/blog\/wp-json\/wp\/v2\/posts\/6886\/revisions"}],"wp:attachment":[{"href":"https:\/\/preposterousuniverse.com\/blog\/wp-json\/wp\/v2\/media?parent=6886"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/preposterousuniverse.com\/blog\/wp-json\/wp\/v2\/categories?post=6886"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/preposterousuniverse.com\/blog\/wp-json\/wp\/v2\/tags?post=6886"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}